Genome Engineering

Rethinking the (Im)Possible, or Biological Plausibility Is Not What You Thought It Was (lecture to the School of Electrical Engineering and Computer Science, Queen Mary University, London, October 26, 2011)

Cognitive Aspects of Genome Function (lecture to Symposium on Neurobiological Correlates of Interpersonal Relations, Freiburg, Germany, October 15, 2011)

Cell Action in Evolution (.pdf file)
Darwin Day lecture, E. Illinois University, Feb. 10, 2011

Revisiting evolution in the 21st Century
Works of the Mind Lecture .pdf file

Revisiting evolution in the 21st Century
Works of the Mind lecture MPEG 4 file (1h42min).

The Basic Program of Liberal Education for Adults
University of Chicago Graham School Lecture date: 3 October 2010

Suggested Readings relevant to a 21st Century view of evolution  (from Scientific American and other general reader sources)

Shapiro JA. 2010. Mobile DNA and evolution in the 21st Century. Mobile DNA, 1:4.

Shapiro JA. 2009. Letting E. coli teach me about genome engineering, Genetics 183:1205–1214

A signal-responsive (cognitive) systems view of the genome, lecture presented at a workshop on "Complexity of the Gene Concept," Santa Fe Institute, March 9-11, 2009

Revisiting the Central Dogma in the 21st Century, 2009, Ann NY Acad Sci 1178: 6-28; lecture presented to a workshop on Natural Genome Engineering & Natural Genome Editing, Salzburg, July 2-6, 2008

Contextualization and Classification of Natural Genetic Engineering Operators, lecture to the Evolutionary Computation Group, University of Essex, June 22, 2007

Barbara McClintock, a 21st Century Biologist, lecture to Botanical Society of America, Chicago, July 10, 2007

Lectures at FOGA 2007, Foundations of Genetic Algorithms IX, Mexico City, 8-11 January 2007

Shapiro JA. 2006. Genome informatics: The role of DNA in cellular computations. Biological Theory 1(3): 288-301.

Why Repetitive DNA is Essential to Genome Function (2005)

A 21st Century View of Evolution (2005)

Genome Formatting for Computation and Function (2002

Lectures at the Institute for Theoretical Physics, UC Santa Barbara, March, 2001

    Thinking about Genome System Architecture
    Natural Genetic Engineering -- the Toolbox for Evolution: Prokaryotes
    Natural Genetic Engineering -- The Toolbox for Evolution - Eukaryotes

A Third Way (Alternatives to Creationism and Darwinism, 1997)

Natural Genetic Engineering and Adaptive Mutation (1997)