[ James A. Shapiro ] James A. Shapiro

Translesion “mutator” polymerases

(Brotcorne-Lannoye and Maenhaut-Michel 1986; Maenhaut-Michel and Caillet-Fauquet 1990; Maenhaut-Michel, Janel-Bintz et al. 1992; Sommer, Knezevic et al. 1993; Kim, Maenhaut-Michel et al. 1997; Reuven, Arad et al. 1999; Wagner, Gruz et al. 1999; Napolitano, Janel-Bintz et al. 2000; Kim, Matsui et al. 2001; Lawrence and Maher 2001; Lawrence and Maher 2001; Fuchs, Fujii et al. 2004; Plosky and Woodgate 2004; Prakash, Johnson et al. 2005; Kuban, Banach-Orlowska et al. 2006; Shcherbakova and Fijalkowska 2006; Fuchs and Fujii 2007; Fujii and Fuchs 2007; Jia, Geacintov et al. 2008; Koskiniemi and Andersson 2009; Sabouri and Johansson 2009; Waters, Minesinger et al. 2009; Andersson, Koskiniemi et al. 2010; Arana and Kunkel 2010; Eoff, Choi et al. 2010; Hastings, Hersh et al. 2010; Hirota, Sonoda et al. 2010; Ho and Scharer 2010; Hoffmann and Cazaux 2010; Livneh, Ziv et al. 2010; Patel, Jiang et al. 2010; Eccles, O'Neill et al. 2011; Herr, Williams et al. 2011; Sage and Harrison 2011)




Andersson, D. I., S. Koskiniemi, et al. (2010). "Biological roles of translesion synthesis DNA polymerases in eubacteria." Mol Microbiol 77(3): 540-548. http://www.ncbi.nlm.nih.gov/pubmed/20609084.

Arana, M. E. and T. A. Kunkel (2010). "Mutator phenotypes due to DNA replication infidelity." Semin Cancer Biol 20(5): 304-311. http://www.ncbi.nlm.nih.gov/pubmed/20934516.

Brotcorne-Lannoye, A. and G. Maenhaut-Michel (1986). "Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB gene." Proc Natl Acad Sci U S A 83(11): 3904-3908. http://www.ncbi.nlm.nih.gov/pubmed/2940594.

Eccles, L. J., P. O'Neill, et al. (2011). "Delayed repair of radiation induced clustered DNA damage: friend or foe?" Mutat Res 711(1-2): 134-141. http://www.ncbi.nlm.nih.gov/pubmed/21130102.

Eoff, R. L., J. Y. Choi, et al. (2010). "Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage." J Nucleic Acids 2010. http://www.ncbi.nlm.nih.gov/pubmed/20936119.

Fuchs, R. P. and S. Fujii (2007). "Translesion synthesis in Escherichia coli: lessons from the NarI mutation hot spot." DNA Repair (Amst) 6(7): 1032-1041. http://www.ncbi.nlm.nih.gov/pubmed/17403618.

Fuchs, R. P., S. Fujii, et al. (2004). "Properties and functions of Escherichia coli: Pol IV and Pol V." Adv Protein Chem 69: 229-264. http://www.ncbi.nlm.nih.gov/pubmed/15588845.

Fujii, S. and R. P. Fuchs (2007). "Interplay among replicative and specialized DNA polymerases determines failure or success of translesion synthesis pathways." J Mol Biol 372(4): 883-893. http://www.ncbi.nlm.nih.gov/pubmed/17707403.

Hastings, P. J., M. N. Hersh, et al. (2010). "Competition of Escherichia coli DNA polymerases I, II and III with DNA Pol IV in stressed cells." PLoS One 5(5): e10862. http://www.ncbi.nlm.nih.gov/pubmed/20523737.

Herr, A. J., L. N. Williams, et al. (2011). "Antimutator variants of DNA polymerases." Crit Rev Biochem Mol Biol. http://www.ncbi.nlm.nih.gov/pubmed/21977975.

Hirota, K., E. Sonoda, et al. (2010). "Simultaneous disruption of two DNA polymerases, Poleta and Polzeta, in Avian DT40 cells unmasks the role of Poleta in cellular response to various DNA lesions." PLoS Genet 6(10). http://www.ncbi.nlm.nih.gov/pubmed/20949111.

Ho, T. V. and O. D. Scharer (2010). "Translesion DNA synthesis polymerases in DNA interstrand crosslink repair." Environ Mol Mutagen 51(6): 552-566. http://www.ncbi.nlm.nih.gov/pubmed/20658647.

Hoffmann, J. S. and C. Cazaux (2010). "Aberrant expression of alternative DNA polymerases: a source of mutator phenotype as well as replicative stress in cancer." Semin Cancer Biol 20(5): 312-319. http://www.ncbi.nlm.nih.gov/pubmed/20934518.

Jia, L., N. E. Geacintov, et al. (2008). "The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions." Nucleic Acids Res 36(20): 6571-6584. http://www.ncbi.nlm.nih.gov/pubmed/18931375.

Kim, S. R., G. Maenhaut-Michel, et al. (1997). "Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA." Proc Natl Acad Sci U S A 94(25): 13792-13797. http://www.ncbi.nlm.nih.gov/pubmed/9391106.

Kim, S. R., K. Matsui, et al. (2001). "Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli." Mol Genet Genomics 266(2): 207-215. http://www.ncbi.nlm.nih.gov/pubmed/11683261.

Koskiniemi, S. and D. I. Andersson (2009). "Translesion DNA polymerases are required for spontaneous deletion formation in Salmonella typhimurium." Proc Natl Acad Sci U S A 106(25): 10248-10253. http://www.ncbi.nlm.nih.gov/pubmed/19525399.

Kuban, W., M. Banach-Orlowska, et al. (2006). "Role of DNA polymerase IV in Escherichia coli SOS mutator activity." J Bacteriol 188(22): 7977-7980. http://www.ncbi.nlm.nih.gov/pubmed/16980447.

Lawrence, C. W. and V. M. Maher (2001). "Eukaryotic mutagenesis and translesion replication dependent on DNA polymerase zeta and Rev1 protein." Biochem Soc Trans 29(Pt 2): 187-191. http://www.ncbi.nlm.nih.gov/pubmed/11356151.

Lawrence, C. W. and V. M. Maher (2001). "Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p." Philos Trans R Soc Lond B Biol Sci 356(1405): 41-46. http://www.ncbi.nlm.nih.gov/pubmed/11205328.

Livneh, Z., O. Ziv, et al. (2010). "Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis." Cell Cycle 9(4): 729-735. http://www.ncbi.nlm.nih.gov/pubmed/20139724.

Maenhaut-Michel, G. and P. Caillet-Fauquet (1990). "Genetic control of the UV-induced SOS mutator effect in single- and double-stranded DNA phages." Mutat Res 230(2): 241-254. http://www.ncbi.nlm.nih.gov/pubmed/2165215.

Maenhaut-Michel, G., R. Janel-Bintz, et al. (1992). "A umuDC-independent SOS pathway for frameshift mutagenesis." Mol Gen Genet 235(2-3): 373-380. http://www.ncbi.nlm.nih.gov/pubmed/1465109.

Napolitano, R., R. Janel-Bintz, et al. (2000). "All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis." Embo J 19(22): 6259-6265. http://www.ncbi.nlm.nih.gov/pubmed/11080171.

Patel, M., Q. Jiang, et al. (2010). "A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V." Crit Rev Biochem Mol Biol 45(3): 171-184. http://www.ncbi.nlm.nih.gov/pubmed/20441441.

Plosky, B. S. and R. Woodgate (2004). "Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases." Curr Opin Genet Dev 14(2): 113-119. http://www.ncbi.nlm.nih.gov/pubmed/15196456.

Prakash, S., R. E. Johnson, et al. (2005). "Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function." Annu Rev Biochem 74: 317-353. http://www.ncbi.nlm.nih.gov/pubmed/15952890.

Reuven, N. B., G. Arad, et al. (1999). "The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication." J Biol Chem 274(45): 31763-31766. http://www.ncbi.nlm.nih.gov/pubmed/10542196.

Sabouri, N. and E. Johansson (2009). "Translesion synthesis of abasic sites by yeast DNA polymerase epsilon." J Biol Chem 284(46): 31555-31563. http://www.ncbi.nlm.nih.gov/pubmed/19776424.

Sage, E. and L. Harrison (2011). "Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis and cell survival." Mutat Res 711(1-2): 123-133. http://www.ncbi.nlm.nih.gov/pubmed/21185841.

Shcherbakova, P. V. and I. J. Fijalkowska (2006). "Translesion synthesis DNA polymerases and control of genome stability." Front Biosci 11: 2496-2517. http://www.ncbi.nlm.nih.gov/pubmed/16720328.

Sommer, S., J. Knezevic, et al. (1993). "Induction of only one SOS operon, umuDC, is required for SOS mutagenesis in Escherichia coli." Mol Gen Genet 239(1-2): 137-144. http://www.ncbi.nlm.nih.gov/pubmed/8510643.

Wagner, J., P. Gruz, et al. (1999). "The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis." Mol Cell 4(2): 281-286. http://www.ncbi.nlm.nih.gov/pubmed/10488344.

Waters, L. S., B. K. Minesinger, et al. (2009). "Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance." Microbiol Mol Biol Rev 73(1): 134-154. http://www.ncbi.nlm.nih.gov/pubmed/19258535.