Table 1F. Genome Formatting for Replication
Formatting signal	Function	References
Origin of replication (Ori)	Permit formation of intiating replication complex on duplex DNA	(Robinson and Bell 2007; Berbenetz, Nislow et al. 2010; Cayrou, Coulombe et al. 2010; Duderstadt, Chuang et al. 2011)
Terminus (Ter)	Allow completion of circular DNA replication	(Jensen 2006; Mercier, Petit et al. 2008; Cayrou, Coulombe et al. 2010; Toro and Shapiro 2010)
Site-specific recombination site (dix, par)	Permit the resolution of dimeric circular replication products into two monomeric circles for partition to daughter cells	(Salje and Lowe 2008; Schumacher 2008; Cortez, Quevillon-Cheruel et al. 2010)
Okazaki primer initiation sites	Facilitate RNA primer synthesis on lagging strand	(Masai and Arai 1996; Lia, Michel et al. 2012)
Telomeric hairpin loop with resolution sites	Continuous DNA strand at the end of a linear genomic molecule (prokaryotes) to permit complete replication of the lagging strand end and separation into two linear copies	(Chaconas 2005; Kobryn, Burgin et al. 2005; Tourand, Deneke et al. 2009; Chaconas and Kobryn 2010)
Telomere	Specialized structure at the end of eukaryotic linear molecules that allow extension of the lagging strand by the telomerase reverse transcriptase	(Blackburn, Greider et al. 1989; Greider and Blackburn 1996; Fajkus, Sykorova et al. 2005; Lamb, Yu et al. 2007; Witzany 2007; Schoeftner and Blasco 2010; Rubtsova, Vasilkova et al. 2012)

 

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