[ James A. Shapiro ] James A. Shapiro


Ig Class (isotype) switching

(Zan, Cerutti et al. 1999; Muramatsu, Kinoshita et al. 2000; Honjo, Kinoshita et al. 2002; Zhang 2003; Li, Woo et al. 2004; Dudley, Chaudhuri et al. 2005; Longerich, Basu et al. 2006; Chaudhuri, Basu et al. 2007; Yan, Boboila et al. 2007; Jolly, Cook et al. 2008; Zan and Casali 2008; Dinkelmann, Spehalski et al. 2009; Doi, Kato et al. 2009; Hackney, Misaghi et al. 2009; Kotnis, Du et al. 2009; Kuang, Luo et al. 2009; Park, Zan et al. 2009; Sellars, Reina-San-Martin et al. 2009; Boboila, Yan et al. 2010; Daniel, Santos et al. 2010; Ise, Kohyama et al. 2011; Okazaki, Okawa et al. 2011)

REFERENCES

 

Boboila, C., C. Yan, et al. (2010). "Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4." J Exp Med 207(2): 417-427. http://www.ncbi.nlm.nih.gov/pubmed/20142431.

Chaudhuri, J., U. Basu, et al. (2007). "Evolution of the immunoglobulin heavy chain class switch recombination mechanism." Adv Immunol 94: 157-214. http://www.ncbi.nlm.nih.gov/pubmed/17560275.

Daniel, J. A., M. A. Santos, et al. (2010). "PTIP Promotes Chromatin Changes Critical for Immunoglobulin Class Switch Recombination." Science 329(5994): 917-923. http://www.ncbi.nlm.nih.gov/pubmed/20671152.

Dinkelmann, M., E. Spehalski, et al. (2009). "Multiple functions of MRN in end-joining pathways during isotype class switching." Nat Struct Mol Biol 16(8): 808-813. http://www.ncbi.nlm.nih.gov/pubmed/19633670.

Doi, T., L. Kato, et al. (2009). "The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination." Proc Natl Acad Sci U S A 106(8): 2758-2763. http://www.ncbi.nlm.nih.gov/pubmed/19202055.

Dudley, D. D., J. Chaudhuri, et al. (2005). "Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences." Adv Immunol 86: 43-112. http://www.ncbi.nlm.nih.gov/pubmed/15705419.

Hackney, J. A., S. Misaghi, et al. (2009). "DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination." Adv Immunol 101: 163-189. http://www.ncbi.nlm.nih.gov/pubmed/19231595.

Honjo, T., K. Kinoshita, et al. (2002). "Molecular mechanism of class switch recombination: linkage with somatic hypermutation." Annu Rev Immunol 20: 165-196. http://www.ncbi.nlm.nih.gov/pubmed/11861601.

Ise, W., M. Kohyama, et al. (2011). "The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells." Nat Immunol 12(6): 536-543. http://www.ncbi.nlm.nih.gov/pubmed/21572431.

Jolly, C. J., A. J. Cook, et al. (2008). "Fixing DNA breaks during class switch recombination." J Exp Med 205(3): 509-513. http://www.ncbi.nlm.nih.gov/pubmed/18332183\.

Kotnis, A., L. Du, et al. (2009). "Non-homologous end joining in class switch recombination: the beginning of the end." Philos Trans R Soc Lond B Biol Sci 364(1517): 653-665. http://www.ncbi.nlm.nih.gov/pubmed/19008195.

Kuang, F. L., Z. Luo, et al. (2009). "H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination." Proc Natl Acad Sci U S A 106(13): 5288-5293. http://www.ncbi.nlm.nih.gov/pubmed/19276123.

Li, Z., C. J. Woo, et al. (2004). "The generation of antibody diversity through somatic hypermutation and class switch recombination." Genes Dev 18(1): 1-11. http://www.ncbi.nlm.nih.gov/pubmed/14724175.

Longerich, S., U. Basu, et al. (2006). "AID in somatic hypermutation and class switch recombination." Curr Opin Immunol 18(2): 164-174. http://www.ncbi.nlm.nih.gov/pubmed/16464563.

Muramatsu, M., K. Kinoshita, et al. (2000). "Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme." Cell 102(5): 553-563. http://www.ncbi.nlm.nih.gov/pubmed/11007474.

Okazaki, I. M., K. Okawa, et al. (2011). "Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation." Proc Natl Acad Sci U S A 108(19): 7920-7925. http://www.ncbi.nlm.nih.gov/pubmed/21518874.

Park, S. R., H. Zan, et al. (2009). "HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation." Nat Immunol 10(5): 540-550. http://www.ncbi.nlm.nih.gov/pubmed/19363484.

Sellars, M., B. Reina-San-Martin, et al. (2009). "Ikaros controls isotype selection during immunoglobulin class switch recombination." J Exp Med 206(5): 1073-1087. http://www.ncbi.nlm.nih.gov/pubmed/19414557.

Yan, C. T., C. Boboila, et al. (2007). "IgH class switching and translocations use a robust non-classical end-joining pathway." Nature 449(7161): 478-482. http://www.ncbi.nlm.nih.gov/pubmed/17713479.

Zan, H. and P. Casali (2008). "AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID." Mol Immunol 46(1): 45-61. http://www.ncbi.nlm.nih.gov/pubmed/18760480.

Zan, H., A. Cerutti, et al. (1999). "Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation." J Immunol 162(6): 3437-3447. http://www.ncbi.nlm.nih.gov/pubmed/10092799.

Zhang, K. (2003). "Accessibility control and machinery of immunoglobulin class switch recombination." J Leukoc Biol 73(3): 323-332. .